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Sheng-Lin Ma Selected Research

Gefitinib (Iressa)

1/2017Capilliposide from Lysimachia capillipes inhibits AKT activation and restores gefitinib sensitivity in human non-small cell lung cancer cells with acquired gefitinib resistance.
3/2016Paris Saponins enhance radiosensitivity in a gefitinib-resistant lung adenocarcinoma cell line by inducing apoptosis and G2/M cell cycle phase arrest.
6/2014Paris saponin I induces apoptosis via increasing the Bax/Bcl-2 ratio and caspase-3 expression in gefitinib-resistant non-small cell lung cancer in vitro and in vivo.
6/2011P21 (waf1/cip1) is required for non-small cell lung cancer sensitive to Gefitinib treatment.
10/2009Combined treatment with TNF-alpha/gefitinib alleviates the resistance to gefitinib in PC-9 cells.

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Sheng-Lin Ma Research Topics

Disease

14Neoplasms (Cancer)
02/2024 - 10/2009
13Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
08/2021 - 05/2007
9Lung Neoplasms (Lung Cancer)
06/2020 - 10/2009
5Neoplasm Metastasis (Metastasis)
08/2021 - 02/2016
3Hepatocellular Carcinoma (Hepatoma)
09/2016 - 01/2014
2Adenocarcinoma of Lung
02/2024 - 03/2016
2Hyperthermia
05/2019 - 08/2018
2B-Cell Lymphoma (Lymphoma, B Cell)
03/2016 - 06/2014
1Inflammation (Inflammations)
02/2024
1Colonic Neoplasms (Colon Cancer)
01/2019
1Ataxia Telangiectasia (Louis Bar Syndrome)
08/2018
1Brain Neoplasms (Brain Tumor)
02/2017
1Glioma (Gliomas)
01/2017
1Hepatitis B
09/2016
1Sarcoma (Soft Tissue Sarcoma)
02/2016
1Adenocarcinoma
02/2012
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
02/2012

Drug/Important Bio-Agent (IBA)

5Proteins (Proteins, Gene)FDA Link
06/2020 - 11/2011
5Gefitinib (Iressa)FDA Link
01/2017 - 10/2009
2Cadherins (E-Cadherin)IBA
08/2021 - 01/2019
2Messenger RNA (mRNA)IBA
01/2017 - 02/2012
2LC capilliposideIBA
01/2017 - 01/2014
1CrizotinibIBA
02/2024
1lorlatinibIBA
02/2024
1brigatinibIBA
02/2024
1alectinibIBA
02/2024
1Histamine Receptors (Histamine Receptor)IBA
08/2021
1Fibronectins (Fibronectin)IBA
08/2021
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
08/2021
1Antineoplastic Agents (Antineoplastics)IBA
06/2020
1chalcomoracinIBA
06/2020
1Radiation-Sensitizing AgentsIBA
06/2020
1Oxygen (Dioxygen)IBA
05/2019
1GemcitabineFDA Link
05/2019
1VimentinIBA
01/2019
1Reactive Oxygen Species (Oxygen Radicals)IBA
08/2018
1Matrix Metalloproteinases (MMPs)IBA
08/2018
1Phosphotransferases (Kinase)IBA
08/2018
1AfatinibIBA
02/2017
1MicroRNAs (MicroRNA)IBA
01/2017
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
01/2017
1CurcuminIBA
01/2017
1VitronectinIBA
09/2016
1Carboplatin (JM8)FDA LinkGeneric
04/2016
1Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
04/2016
1Paclitaxel (Taxol)FDA LinkGeneric
04/2016
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
04/2016
1EndostatinsIBA
04/2016
1SaponinsIBA
03/2016
1Cytosine DeaminaseIBA
05/2015
1Flucytosine (Ancobon)FDA Link
05/2015
1polyphyllin DIBA
06/2014
1bcl-2-Associated X Protein (bcl 2 Associated X Protein)IBA
06/2014
1Caspase 3 (Caspase-3)IBA
06/2014
1Glucose (Dextrose)FDA LinkGeneric
06/2014
1Sorafenib (BAY 43-9006)FDA Link
01/2014
1Indicators and Reagents (Reagents)IBA
01/2013
1Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA
01/2013
1Docetaxel (Taxotere)FDA Link
01/2013
1Pemetrexed (MTA)FDA Link
01/2013
1DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA
11/2011
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
06/2011
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
10/2009
1yiguanIBA
05/2007

Therapy/Procedure

6Therapeutics
06/2020 - 02/2012
3Radiotherapy
06/2020 - 02/2016
2Chinese Traditional Medicine (Traditional Chinese Medicine)
01/2019 - 11/2011
1Immunotherapy
06/2018
1Precision Medicine
01/2017
1Chemoradiotherapy
04/2016
1Drug Therapy (Chemotherapy)
05/2007